In 1649 a French expedition of 203 men from Martinique led by Jacques du Parquet founded a permanent settlement on Grenada. Within months this led to conflict with the local islanders which lasted until 1654 when the island was completely subjugated by the French.[11] The indigenous islanders who survived either left for neighbouring islands or retreated to remoter parts of Grenada where they were marginalised—the last distinct communities disappeared during the 1700s.
Warfare continued during the 1600s between the French on Grenada and the Caribs of present-day Dominica and St. Vincent and the Grenadines. The French named their new colony La Grenade, and the economy was initially based on sugar cane and indigo. The French established a capital known as Fort Royal (later St. George). To shelter from hurricanes the French navy would often take refuge in the capital's natural harbour, as no nearby French islands had a natural harbour to compare with that of Fort Royal. The British captured Grenada during the Seven Years' War in 1762.